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IGF-1 LR3 retains the ability to bind IGF-1 and insulin receptors but has reduced binding affinity to insulin-like growth factor-binding proteins (IGFBPs)

doi: 10.1016/j.theriogenology.2019.03.016 88 RizzoG.BaroniL.LombardoM

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38 Iron overload Although iron is a helpful component of the human body and the major micronutrient in the human diet, involved in crucial cellular functions and metabolic processes, excessive iron increases the production of ROS, leading to cell dysfunction or death, tissue damage, and organ disease

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The obtained amplitude weighted averaged lifetime, Av Amp , values were averaged for the set and used to plot the K d curves